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Protein Misfolding and Aggregation The main histopathological features of AD are amyloid plaques and neurofibrillary tangles (NFTs), which are formed as a result of misfolding of the amyloid-β peptide (Aβ) and tau protein (τ)
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Increased levels of GSH within tumor cells are implicated in conferring resistance to chemotherapy drugs, including cisplatin [14]
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