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TAC-001, a toll-like receptor 9 (TLR9) agonist antibody conjugate targeting B cells, promotes anti-tumor immunity and favorable safety profile following systemic administration in preclinical models
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272 In a follow-up study, the same compound was studied for affinity for other galectin receptors ( K D = 370 μM for Gal-1, 1000 μM for Gal-7, 900 μM for Gal-8N, and 370 μM for Gal-9N, the N-terminal domain of Gal-9)
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