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They used the mitochondrial biogenesis inducer N -[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide (SRT1720) to successfully increase peroxisome proliferator-activated receptor γ (PPARγ) coactivator 1-α expression and liver regeneration, thereby preventing advanced liver damage after APAP overdose (Du et al., 2017a)
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