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84,109,110 The 4-kDa fluorescein isothiocyanate-dextran (4-kDa FITC-dextran) is generally used as a probe for investigating leak pathway permeability
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This commenter stated that requiring support for such “generic” measures would impose unnecessary burden without meaningful benefit, and recommended flexibility for QCDRs and qualified registries to determine whether broadly applicable measures add value for their clinicians
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