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The study also revealed that MeCbl worked by inhibiting certain inflammatory pathways in the spinal cord, which are activated by vincristine, thereby balancing pro-inflammatory and anti-inflammatory signals
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Class A GPCRs (e.g., β 2 -AR, α 1B , m-opioid receptor, V2 receptor) transiently interact with β -Arr mostly at the plasma membrane and display transient internalization
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