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glutathione peroxidase 1 hydroxynonenal Valentine
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glutathione peroxidase 1 hydroxynonenal Valentine

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Studies have confirmed that lactylation can affect the glycolysis and oxidative phosphorylation pathways of B cells ( 6 Regulation of immune responses by lactylation It has been found that the downregulation of the methylglyoxal metabolic enzyme GLO2 in immune cells leads to the accumulation of the metabolic molecule SLG ( In SLE, lactylation of cGAS induced by mitochondrial DNA activates the interferon response, promoting the production of autoantibodies (72), enhancing the expression of genes related to B cell differentiation and antibody secretion

glutathione peroxidase 1 hydroxynonenal Valentine

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