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5 Amino 1MQ and MOTS-C (fat loss and muscle gain plateau) Comment βMUSCLEβ for the research 2023 study by Li in Nature Metabolism showed 38% reduction in fat mass and 22% increase
After being fed HFD for a total of 16-weeks (an appropriate rodent model of DIO and comparable to human obesity [21]) and reaching pre-arrival body weights (~38g), mice were randomized into balanced control and treatment cohorts (n=9/cohort), with similar group average body weight and standard deviation
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5-Amino-1MQ vs AOD-9604: Key Takeaways 5-Amino-1MQ and AOD-9604 are both powerful fat-loss agents β but their strengths come from entirely different mechanisms: β 5-Amino-1MQ β Inhibits NNMT to preserve NADβΊ, activate SIRT1, elevate basal metabolic rate, and improve metabolic flexibility (Kraus et al., Nature Medicine )
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