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As a practical example, network pharmacology can first overlap PD oxidative-stress gene modules with target sets of MFH actives to nominate shortlists of 2–3 component pairs (e.g., Rg1 + EGCG, or APS + CUR) that co-cover Nrf2/ARE and PI3K/Akt while dampening NF-κB
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The only circumstances in which I wouldn't recommend cyanocobalamin is if there is a family history of lebers syndrome (quite a rare hyper-sensitivity to the cyano molecule
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