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A concentrated brightening cream that combines four of the most effective skin-lightening actives in one formula. Glutathione and Alpha Arbutin inhibit the enzyme responsible for melanin production, while Kojic Acid accelerates fading
To generate the cytoplasm-targeted (suffix, _cyto) variants, we used Gibson assembly (Gibson et al., 2009) to remove existing N- and C-terminal tags and incorporated an N-terminal strong nuclear exclusion sequence (NES
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[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Stacker S.A., Stenvers K., Caesar C., Vitali A., Domagala T., Nice E., Roufail S., Simpson R.J., Moritz R., Karpanen T., et al
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