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Tolerance-inducing therapies in coeliac disease — mechanisms, progress and future directions | Nature Reviews Gastroenterology & Hepatology
Specifically, genomic instability characteristic of many cancers including GBM elicit engagement of the cyclic guanosine monophosphate (GMP) adenosine monophosphate (AMP) synthase (cGAS)- stimulator of IFN genes (STING) pathway which prompts secretion of type one interferon (IFN) into the TME [154, 155]
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