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Glutathione Metabolism - an overview
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Studies conducted at the cellular level have demonstrated that in Huh-7/SRE-Luc cells, curcumin broadly inhibits the transcription of SREBP target genes, including nine fatty acid and triglyceride synthesis genes (such as SREBP-1, FAS, ACC1, and SCD-1) as well as eleven cholesterol synthesis-related genes (including SREBP-2, HMGCR, HMGCS, and MVK), resulting in a marked reduction in cholesterol and triglyceride levels [93]
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