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The company revealed topline results from trials in the second half of 2024, with a planned New Drug Application (NDA) submission in the first quarter of 2025
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Moreover, dysbiosis alters microbial metabolites, including short-chain fatty acids (SCFAs), trimethylamine N-oxide (TMAO), and indoles, which disrupts endocrine signaling (PYY, GLP-1/2, adiponectin, and resistin), impairs insulin pathways, and promotes lipogenesis, ultimately driving obesity and diabetes (Moszak et al., 2020)
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