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“When a big company takes over a little company, they pick out the bits that they think fit what they want, and leave the rest,” said Michael Parnham, who was a senior scientific adviser at PLIVA at the time of the acquisition by GSK
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In gastric L-cells, the bioactive forms of GLP-1, GLP 7–37 (glycine-extended GLP-1), and GLP 7–37 amide , are cleaved from its precursor (pre)proglucagon by prohormone convertase (PC)1 and PC3, which co-generates GLP-2 and oxyntomodulin
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