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ψ = reduced peptide bond (CH 2 -NH 2 ) Family # Ri- R3 1 2 3 1 hexanoyl pb pb pb heptanoyl Y pb pb pb pentanoyl Y pb pb pb butanoyl Y pb pb pb propanoyl Y pb pb pb acetanoyl Y pb pb pb isopropanoyl Y pb pb pb tert-butanoyl Y pb pb pb isobutanoyl Y pb pb pb benzoyl Y pb pb pb hexanoyl Y ψ pb pb heptanoyl Y Ψ P b P b pentanoyl Y ψ pb pb butanoyl Y ψ pb pb propanoyl Y ψ pb pb acetanoyl Y ψ pb pb isopropanoyl Y ψ pb pb tert-butanoyl Y ψ pb pb isobutanoyl Y ψ pb pb benzoyl Y ψ pb pb hexanoyl 5 ψ pb ψ heptanoyl 5 ψ pb ψ pentanoyl 5 ψ pb ψ butanoyi 5 ψ pb ψ propanoyl 5 ψ pb ψ acetanoyl 5 ψ pb ψ isopropanoyl 5 ψ pb ψ tert-butanoyl 5 ψ pb ψ isobutanoyl 5 ψ pb ψ benzoyl 5 ψ pb φ hexanoyl 5 pb pb ψ heptanoyl 5 pb pb ψ pentanoyl 5 pb pb ψ butanoyi 5 pb pb ψ propanoyl 5 pb pb ψ acetanoyl 5 pb pb ψ isopropanoyl 5 pb pb ψ tert-butanoyl 5 pb b ψ isobutanoyl 5 pb pb ψ benzoyl 5 pb pb ψ hexanoyl 5 pb pb pb heptanoyl 5 pb pb pb pentanoyl 5 pb pb pb butanoyi 5 pb pb pb propanoyl 5 pb pb pb acetanoyl 5 pb pb pb isopropanoyl 5 pb pb pb tert-butanoyl 5 pb pb pb isobutanoyl 5 p pb pb benzoyl F I 5 pb pb pb hexanoyl ψ pb pb heptanoyl ψ pb pb pentanoyl ψ pb pb butanoyl ψ pb pb propanoyl νμ pb pb acetanoyl ψ pb pb isopropanoyl ψ pb pb tert-butanoyl ψ pb pb isobutanoyl ψ pb pb benzoyl ψ pb pb hexanoyl ψ pb ψ heptanoyl Ψ P b Ψ pentanoyl ψ pb ψ butanoyl ψ pb ψ propanoyl ψ pb ψ acetanoyl ψ pb ψ isopropanoyl ψ pb ψ tert-butanoyl ψ pb ψ isobutanoyl ψ pb ψ benzoyl ψ pb ψ hexanoyl pb pb ψ heptanoyl pb pb ψ pentanoyl pb pb ψ butanoyl pb pb ψ propanoyl pb pb ψ acetanoyl pb pb ψ isopropanoyl pb pb ψ tert-butanoyl F pb pb ψ isobuianoyl F pb pb ψ benzoyl F 5 pb pb ψ hexanoyl C pb pb pb heptanoyl C pb pb pb pentanoyl c pb pb pb butanoyl c pb pb pb propanoyl c pb pb pb acetanoyl c pb b pb isopropanoyl c pb pb pb tert-butanoyl c pb pb pb isobutanoyl c pb pb pb benzoyl c pb pb pb hexanoyl C Ψ Pb pb heptanoyl C ψ pb pb pentanoyl C ψ pb pb butanoyl c ψ pb pb propanoyl c ψ pb pb acetanoyl c ψ pb pb isopropanoyl c ψ pb pb tert-butanoyl c 5 ψ pb pb isobutanoyl c ψ pb pb benzoyl c ψ pb pb hexanoyl C ψ pb ψ heptanoyl C ψ pb ψ pentanoyl c ψ pb ψ butanoyl c ψ pb ψ propanoyl c ψ pb ψ ψ pb ψ ψ pb ψ ψ pb ψ ψ pb ψ ψ pb ψ hexanoyl C pb pb ψ heptanoyl C pb pb ψ pentanoyl C pb pb ψ butanoyl C pb pb ψ propanoyl C pb pb ψ acetanoyl c pb pb ψ isopropanoyl c pb pb ψ tert-butanoyl c pb pb ψ isobutanoyl c pb b ψ benzoyl c pb pb νμ 1 -16 Same pattern as families I -4 with R2=S 17-20 Same pattern as families 1 -4 with R2-T 21 -24 Same pattern as families 1 -4 with R2=D 25-28 Same pattern as families 1 -4 with R2=E 29-32 Same pattern as families 1 -4 with R2=Y, R3=V 33-36 Same pattern as families 1 -4 with R2=F, R3=V 37-40 Same pattern as families 1 -4 with R2= , R3=V 41 -44 Same pattern as families 1 -4 with R2=S, R3=V 45-48 Same pattern as families 1-4 with R2=T, R3=V 49-52 Same pattern as families 1 -4 with R2=D, R3=V 53-56 Same pattern as families 1 -4 with R2=E, R3=V 57-85 Same pattern as families 29-56 with R3=L 86-170 Same pattern as families 1-85 with n=3 342 D-norleucine Y I 5 pb pb pb D-norleucine F I 5 pb pb pb D-norleucine C I 5 pb pb pb D-norleucine S I 5 pb pb pb D-norleucine T I 5 pb pb pb D-norlencine D I 5 pb pb pb D-norleucine E I 5 pb pb pb D-norleucine G I 5 pb pb pb 343 D-norleucine Y I 5 pb pb ψ D-norleucine F I 5 pb pb ψ D-norleucine C I 5 pb pb ψ D-norleucine S I 5 pb pb ψ D-norleucine T 1 5 pb pb ψ D-norleucine D I 5 pb pb ψ D-norleucine E I 5 pb pb ψ D-norleucine G I 5 pb pb ψ 344 D-norleucine Y I 5 ψ pb pb D-norleucine F I 5 ψ pb pb D-norleucine C I 5 Ψ Pb pb D-norleucine S I 5 ψ pb pb D-norleucine T I 5 ψ pb pb D-norleucine D I 5 ψ pb pb D-norleucine E I 5 ψ pb pb D-norleucine G I 5 ψ pb pb 345 D-norleucine Y I 5 ψ pb ψ D-norleucine F I 5 Ψ pb Ψ D-norleucine C I 5 Ψ pb Ψ D-norleucine S I 5 Ψ pb Ψ D-norleucine T I 5 Ψ pb Ψ D-norleucine D I 5 Ψ pb Ψ D-norleucine E I 5 Ψ pb Ψ D-norleucine G I 5 Ψ pb Ψ 346-349 Same pattern as families 342-345 with R3=V 350-353 Same pattern as families 342-345 with R3=L 354-365 Same pattern as families 342-353 with R1=D norvaline 366-377 Same pattern as families 342-345 with R3=D-lysine 378-389 Same pattern as families 342-345 with R3=D-arginine 390-401 Same pattern as families 342-345 with R3=D S-methyl cysteine 402-457 Same pattern as families 342-401 with n=3 458-513 Same pattern as families 342-401 with n=4 514-569 Same pattern as families 342-401 with n=6 Alternatively, the analogs or growth factor mimics of the present invention may also be represented as comprised of four elements joined by covalent peptide or reduced peptide bonds, as follows: I - II - III - rv where I = an acid such as heptanoic, hexanoic, pentanoic, butyric, proprionic, acetic, benzoic, or substituted benzoic acid, and isoforms thereof

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